2016年1月31日星期日

What specific symptoms of polycystic kidney disease have it

Specific symptoms of polycystic kidney disease have what? Polycystic kidney parenchyma numerous cysts of varying sizes, the larger can be large, small ones can only be visible to the naked eye, so that the entire increase in renal volume, surface was rugged cystic projections, light yellow capsule slurry, and sometimes because of bleeding and dark brown or reddish-brown. There are two types of polycystic kidney disease, autosomal recessive polycystic kidney disease and autosomal dominant polycystic kidney disease. So what specific symptoms of polycystic kidney disease have? Here, please come to our nephrologist detailed introduction about it.
What specific symptoms of polycystic kidney disease have it?
1. nephropathy progression of renal enlargement sides asymmetry, there are differences in size, to the late two kidneys may occupy the entire abdominal cavity, renal cysts have a lot of fabric surface, so that kidney-shaped irregular, uneven, hard.
2. important symptom for kidney pain, often for lower back pressure or dull, there are pain, sometimes abdominal pain. Pain may be due to physical activity, walking for too long, sedentary exacerbated after bed reduce. Renal hemorrhage due to move stones or infection is sudden severe pain.
3. About half of patients showed microscopic hematuria hematuria, may have episodes of gross hematuria, the Department of the cyst wall caused by ruptured blood vessels. Bleeding for a long time can cause colic clot through the ureter. White blood cells in urine is often accompanied by hematuria and proteinuria, urinary protein less, usually less than 1.0g / d. Obviously when pyuria kidney infection, hematuria aggravated, low back pain with fever.
4. Hypertension is a common manifestation of ADPKD, not before serum creatinine increased, about half of high blood pressure, which is the cyst oppression surrounding tissue, activation of the renin - angiotensin - aldosterone system related. The past 10 years, Graham PC, Torre V and Chapman AB confirmed that the disease so normal kidney tissue, increased interstitial between the cyst and cyst epithelial cells adjacent renin granules, and renin secretion. These are closely related to the growth of cysts and hypertension. In other words, the emergence of hypertension cyst is growing rapidly, it can directly affect the prognosis.

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