Adult polycystic kidney disease follow the inheritance of it

Adult polycystic kidney disease clinical more common, the incidence rate in one-thousandth to two, and accounted for 5% -10% of end-stage renal failure. The disease follows an autosomal dominant inheritance law, namely 1, male and female incidence equal chance ; 2, the sick one parent, 50% of children get cysts genes and disease, such as parents have this disease, children, the incidence rate increased to 75%; 3, not sick children do not carry the gene cyst, its next generation ( grandchildren) can not develop the disease, that is not atavistic. real situation without the genetic parents and the incidence of the mutations were rare.
First, adult polycystic kidney disease is a genetic disease?
Adult polycystic kidney disease is a genetic disease? Answer: Adult polycystic kidney disease is an autosomal dominant familial disease, full name adult autosomal dominant polycystic kidney disease, is caused by chronic renal failure, One common uremia.
Polycystic kidney cysts may change over time and "Health", when cysts grow to a certain stage, a small passageway connecting the capsule and renal tissue due to clogging, the cyst gradually increasing the liquid can not be excluded. Cyst oppression kidney tissue, resulting in tubular atrophy sclerosis, the ball disappeared, impaired renal function. Kidney capsule kinds of different sizes, from the size of soybeans to the size of eggs, when the growth of abnormal renal cyst squeeze the surrounding tissue, so that the loss of function of normal kidney tissue, resulting in renal dysfunction, chronic renal failure, or even uremia.
Cyst not only violated the kidneys, and can infringe on the liver, pancreas, so patients are often found to have polycystic kidney disease polycystic liver also how exist. Treatment of multi-use needle decompression therapy, but can not cure polycystic kidney disease. Since currently no effective treatment, and therefore dependent on good control of blood pressure, disabled nephrotoxic drugs, protect renal function ,, blood stasis, etc. on delaying the progression of some help.
Second, the clinical manifestations of adult polycystic kidney disease
Adult polycystic kidney cyst that is generally born, but smaller, easy to find, 20 years ago generally difficult to find, but if the family polycystic kidney disease patients, should early detection, regular follow-up. 30-40 years old, cysts grow faster, showing renal covered vesicles of different sizes, with diameters ranging from a few millimeters to several centimeters, liquid capsule with a urine sample.
Patients often appear different clinical manifestations: persistent or paroxysmal waist and abdomen pain, tired after the increase; intermittent gross hematuria; sizes palpable abdominal mass; hypertension with headache and dizziness; urinary urgency dysuria and other urinary Road signs of infection; poor appetite, nausea, vomiting and other manifestations of renal dysfunction. Urinary tract X-ray, B ultrasound, CT, MRI and other tests can help diagnose kidney isotope examination can help assess the extent of kidney damage.

                                                      kidneyhospitalabroad@hotmail.com 
WhatsApp:+8615511395691
Viber:+8615511395691