Polycystic kidney disease characteristics and clinical manifestations

What is polycystic kidney disease? Congenital hereditary polycystic kidney disease, due to its mode of inheritance (16 pairs of autosomal dominant) determines polycystic generations of the family have a genetic predisposition. Polycystic kidney disease recurrence risk: if either parent was polycystic kidney disease patients, each of which give birth to a child have a 50% risk of suffering from polycystic kidney disease opportunities. The disease can be seen at any age, no significant difference in incidence between men and women.

Polycystic kidney shape, visible inside the kidneys have a lot of thin spherical cyst, its diameter is generally from a few millimeters to a few centimeters size, there are bright yellow liquid, when faced with infection or trauma, it becomes bloody fluid. With increasing age, the cyst gradually increased, and to promote the gradual enlargement of the kidneys. From the outside resembles a bunch of kidney ripe grapes. Because of the gradual enlargement of the cyst oppression renal units, causing partial kidney renal obstruction, directly damage the kidney function. As patients age, the cyst gradually increased, gradually increased renal damage, and even the development of renal failure, uremia.

Polycystic kidney disease characteristics

1, adult polycystic kidney disease from birth with multiple cysts, but there are always many patients without clinical manifestations, not the disease, temporarily with special treatment.

2, the general into adulthood began to appear after 30 years of clinical symptoms, earlier age of onset of clinical symptoms more severe, the later the age of onset of clinical symptoms are relatively mild, male heavy women.

3, about 30% of patients with polycystic kidney disease polycystic liver, but the liver function is normal, without any symptoms. Spleen, pancreas, lung, ovarian cysts, etc. will also have the presence of about 2% can occur intracranial vascular malformations and aneurysms exist, can easily lead to intracranial hemorrhage.

4, the patient developed symptoms, general development of renal failure an average of more than 10 years, but there are great individual differences.

Patients with polycystic kidney disease increases with age, the gradual enlargement of the cyst, oppression kidney tissue, affecting kidney function, the earliest manifestations are: blood pressure starts to rise, abnormal urine tests, hematuria or proteinuria. In this, to remind the majority of patients, we must pay attention to the above performance, vigilance, often continuously measure blood pressure, do urine tests, found that more than once show as early as possible to take effective control method, if the cyst rupture, there will be hematuria, should go to hospital for treatment.

What are the clinical manifestations after the onset of polycystic kidney disease have?

Expressive of the following two parts:

First, polycystic kidney itself oppressive influence clinical manifestations of renal function and kidney enlargement, common: abdominal pain, back pain and pulling, nocturia, palpable mass in the abdomen swollen kidneys, 60% of patients have high blood pressure, usually no swelling.

Second, the clinical manifestations of polycystic kidney complications:

Polycystic kidney disease easily broken, easy bleeding, vulnerable and easy stones and other complications, it is prone to partial waist hematuria, stones or blockage caused by blood clots, abdominal pain, abnormal urine tests, urinary tract infections and other symptoms.

Polycystic kidney disease as complicated by brain aneurysm rupture easily lead to severe headache, vomiting, severe symptoms of cerebral vascular accident.

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