Overview of polycystic kidney disease

Polycystic Kidney Disease Overview:

Polycystic kidney disease is a genetic disease. According to genetic characteristics, divided into autosomal dominant polycystic kidney disease (PKD) and autosomal recessive polycystic kidney disease (ARPKD) categories. Autosomal dominant polycystic kidney common. ADPKD is autosomal dominant, which is characterized as having a familial aggregation, may be the disease of men and women, gender involvement opportunities are equal, successive generations can occur in patients. Autosomal dominant polycystic kidney disease, also known as adult polycystic kidney disease, polycystic kidney disease is common. Due to the deepening understanding of the disease, the prognosis is significantly improved. ARPKD is autosomal recessive. Almost all parents equally no history. Autosomal recessive polycystic kidney disease, also known as infantile polycystic kidney disease, a rare type of polycystic kidney disease. Chang died shortly after birth, only a handful of lighter types can survive to childhood or even adults.


PKD symptoms common in adulthood. Cyst has existed at birth, grow up gradually over time, or occur in adulthood and the development has not been fully elucidated. However, most patients with lesions in the fetal period may have existed. The vast majority of renal abnormalities. Inconsistent on both sides of the extent of lesions. Characterized in that: the whole kidney cysts filled with varying sizes, with diameters ranging from just a few centimeters to be able to distinguish. Nipple and cones often illegible. Renal pelvis significant deformation. Liquid capsule with urine, bleeding or infection showed different appearance. Cyst was progressively older, related processes may be associated with cell proliferation, cell secretory function changes and cysts surrounding tissue impairment. PKD after cyst epithelial cells cultured with PKD do not show the same properties: PKD cyst fluid endotoxin or Gram-negative bacteria, but no ARPKD cyst fluid.


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