Polycystic kidney disease diagnostic methods and preventive care

Basic knowledge of polycystic kidney disease
Department of polycystic kidney cortex and medulla appear a hereditary kidney disease countless small bladder. The disease can be seen at any age, no significant difference between men and women. Slice meat with visible kidney cortex and medulla covered with cysts of varying sizes, shape like a bunch of grapes. Sac spherical, cylindrical or prismatic, diameter 0; 1 to several centimeters, capsule filled with liquid, the appearance may be a clear color, also for the redness of the skin, bladder island between the capsule and see a small amount of normal tissue. Swelling of the kidneys than the normal kidney is 5 to 6 times, 10 times the newborn can. Because renal cyst oppression and renal vascular tissue, glomeruli can disappear, tubular atrophy, sclerosis, and finally lead to kidney dysfunction.
Polycystic kidney disease diagnostic methods
Polycystic kidney disease diagnosis is generally not difficult, according to family genetic history (parents, brothers, sisters, children, how cystic diseases, etc.), bilateral renal enlargement and proteinuria diagnosis is made on clinical, ultrasound imaging examination diagnosed decisive effect. Abdomen shows irregular renal contour, irregular increases. Ultrasonography kidneys significantly increased visibility, renal full size ranging from liquid dark area, normal kidney structure disappeared. Further intravenous urography or retrograde pyelography also be helpful in the diagnosis, showing the renal pelvis is elongated, flattened calyx or was half-shaped. I saw a side of early may have changed, but may be due to the late often without developing renal insufficiency, shall be carried out large doses of intravenous urography in order to confirm the diagnosis. Most of it has changed in patients with early kidney concentration function, such as lower specific gravity, urine osmolality decreased, as well as significantly increased urine output; late stage renal insufficiency and uremia.
Adult polycystic kidney disease prevention
Adult polycystic kidney disease known as autosomal dominant polycystic kidney disease, patients usually bilateral renal enlargement, cortex and medulla have multiple liquid cyst formation and increasing secondary renal dysfunction. It can affect multiple systems, such as the digestive system, cardiovascular system, central nervous system, reproductive system, formation of liver cysts, splenic cyst, aneurysm, heart valve abnormalities. The disease often onset in 30-50 years, but according to the latest research shows including the fetus, including any period may be the disease.
Autosomal dominant polycystic kidney laws (ie, adult polycystic kidney disease), the purpose of considering favorably students can do the following:
1, premarital attention B-ultrasound (especially parents who have polycystic kidney disease), and to avoid the risk of both men and women marry this disease, because that would increase the incidence of the next generation;
2, polycystic kidney disease patients should be 10 weeks of pregnancy the amniotic fluid or chorionic villus of "cyst gene" test. Since the disease was 50% of the inheritance of (unilateral sick parents), check the molecular genetics of polycystic kidney disease can help families choose a healthy child, and this child will no longer carry the genes affect future generations. Thus, the disease can be prevented.


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