What are the symptoms of polycystic kidney Late

Late symptoms of polycystic kidney disease is low back pain and hematuria, hand can touch the swollen kidneys. Secondly, the late symptoms of polycystic kidney function failure caused by the performance of its symptoms. Including high blood pressure, anemia, fatigue, high serum creatinine not want to diet, and so on.

Early polycystic kidney disease usually no obvious symptoms. Polycystic kidney cysts increases late stage kidney volume increases, and the emergence of morphological abnormalities, such as renal pelvis shaped, structural integrity renal papillary renal pyramids and other damage. Cyst spherical, large and small.

Renal cyst can just beginning when few, and gradually increased with the progression, and ultimately makes the kidneys occupied by cysts, kidney up to the size of football. In the light microscope, among kidney cyst can still see the complete structure, from the normal performance to glomerulosclerosis, tubular atrophy, interstitial fibrosis varies, these changes are due to compression of renal cysts as ischemia. In the electron microscope, the cyst epithelial cells appear as two kinds of forms: one with the proximal tubule epithelial cells similar to the other is similar to the distal tubule. Cyst fluid are generally more clear, when there is an infection or bleeding cyst can be purulent or bloody.

Polycystic kidneys significantly increased size and weight, around about 10 times normal. Sleek, spindle or columnar section shows cyst, radial distribution. Were columnar epithelial cells, consistent with the collecting duct epithelial cells. Pelvis and calyces of the renal parenchyma is expanded oppression narrowed smaller.

Polycystic kidney cysts will eventually increase as kidney function units complete injury, have cause renal dysfunction and uremia, loss of kidney function.


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